ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2013, Vol. 44 ›› Issue (9): 1342-1348.doi: 10.11843/j.issn.0366-6964.2013.09.002

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The Recent Research Progress and Outlook of Haploid Stem Cell in Mammals

ZHAO Hai-long1, ZHAO Yong-ju2, YANG Li-qun1, XIANG Zhong-huai1, CUI Hong-juan1*   

  1. (1. State Key Laboratory of Silkworm Genome BiologySouthwest UniversityChongqing 400715, China; 2. College of Animal Science and Technology, Southwest University,Chongqing 400715, China)
  • Received:2013-03-22 Online:2013-09-23 Published:2013-09-23

Abstract:

 Haploid embryonic stem (haES) cells contain one single set of chromosome and share some characteristics of normal embryonic stem cells, including the ability of self-renewal in vitro and forming multiple functional cells of all the tissues and organs. Recent studies demonstrate that haES cells are divided into parthenogenetic and androgenetic mouse embryos. Abundant data and evidence show that haES could be used as an ideal tool for genetic analyses. Here, we summary the recent progresses, potential applications, and some limitations of the mammalian haES. We also provide some viewpoints about haES combined with our study.

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